Archive for the ‘Celebrex (Celecoxib)’ Category

Pfizer Drops Celebrex Ads

Sunday, August 30th, 2009

Pfizer Celebrex sales slowed as stock droppedShares of Pfizer stock dropped Monday after the company reaffirmed over the weekend that it will keep selling Celebrex even though it will temporary suspend the drug’s direct-to-consumer advertising.

The company will hold off on the ads until the Food and Drug Administration reviews two recent clinical trials, one of which showed that high doses of Celebrex caused a significantly higher cardiovascular risk compared to patients who took placebos. Pfizer said the result was inconsistent with all other tests, which demonstrated that Celebrex didn’t cause an extra heart-related risk. The tests were measuring Celebrex’s ability to prevent colon polyps.

Pfizer stock may have dropped but Celebrex is still a very powerful and popular arthritis pain relief drug. Thousands of Americans buy celebrex online everyday to treat pain from arthritis without narcotics.

The stock lost 51 cents, or 3.1%, to $24.94 on Monday, after tumbling more than 11% on Friday. Trading volume on Friday was 289.7 million shares, about eight times the normal daily volume. Trading volume Monday was heavy, too, as some 55 million shares were exchanged before noon.

Responding to Food and Drug Administration concerns, Pfizer agreed to suspend television, newspaper and radio advertising on Celebrex, which is in the same class of COX-2 inhibitor as Merck’s (MRK:NYSE) Vioxx, which was pulled off the market on Sept. 30

The FDA said it is leaving its regulatory options open on Celebrex. “We do have great concerns about this product and this class of products,” said acting Commissioner Lester Crawford on Friday.

The agency said doctors should evaluate “alternative therapy,” adding that if doctors believe that patients would benefit from Celebrex that they should prescribe “the lowest effective dose” of the drug.

Although Wall Street’s Pfizer-watchers have prepared their economic models for the worst-case scenario of Pfizer withdrawing Celebrex, most view such action as unlikely. They believe that the toughest response will be a more restrictive label for Celebrex. Another Pfizer COX-2 drug, Bextra, just had its label strengthened to emphasize potential side-effects. In any case, Pfizer’s sales, earnings and stock can expect to get hammered.

Can Fish Oil Supplements Compete With Celebrex?

Tuesday, August 25th, 2009

Fish Oil For Joint PainMore and more studies are coming out showing the benefits of taking fish oil supplements as an anti-inflammatory and pain killer. This is in line with the long list of already known benefits of supplementing with fish oils rich in omega-3 fatty acids.

To Relieve Joint Pain With Prescriptions Drugs; Buy Celebrex Online

Let me explain some of the many benefits of omega-3 fatty acids (fish oil is the best source). Inflammation is present in many diseases such as arthritis, bursitis, and tendinitis, inflammation is what causes the pain in most of these cases. Joint pain in your hands, knees and elsewhere in many cases is caused by inflammation in your joints and over time this can lead to arthritis. Prescription pain killers for joint pain such as COX-2 inhibitors (Celebrex, etc.) have been used by many people to treat arthritis, but there have been recent news stories in the last several years linking them to serious side effects, even in some cases death.

I think this has made many people look to other ways to treat this condition and fish oil supplements as an anti-inflammatory and pain killer is becoming very popular alternative. The omega-3 fatty acids in fish oil has potent anti-inflammatory properties. It can bring about pain relief by bringing down inflammation in the joints. Many studies have shown that people with mild to moderate arthritis can get the most pain relief.

However, using fish oil supplements as an anti-inflammatory and pain killer in cases where there is severe pain will probably not lead to a dramatic relief of pain. But, the omega-3 fatty acids in fish oil have so many other proven health benefits especially regarding heart health that in my opinion most everybody should be taking them on a daily basis. Buying drugs online is very popular, and while fish oil does work for for some, it looks like the masses have opted for celebrex as their pain reliever of choice.

Celebrex Approved For Juvenile Rheumatoid Arthritis

Wednesday, March 18th, 2009

uesc_01_img0050The U.S. Food and Drug Administration (FDA) today approved Celebrex (celecoxib) for the relief of the signs and symptoms of Juvenile Rheumatoid Arthritis (JRA) in patients two years of age and older.  JRA is an autoimmune disease that affects approximately 30,000 to 60,000 children in the United States alone.

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The disease causes joint swelling, pain, decreased range of motion and abnormalities of growth and development. In some instances, systemic complications may occur including uveitis, a chronic inflammation of the eye. In severe, uncontrolled cases, permanent disability may occur due to progressive joint damage!

A 24-week study of Celebrex involving 242 patients between the ages of two and 17 years demonstrated its effectiveness in treating JRA. The most commonly reported side effects were cough, cold, upper respiratory tract infection, abdominal pain, headache, fever, nausea, diarrhea and vomiting.

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Sunday, December 21st, 2008

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Celebrex: What You Need To Know

What is Celebrex?
Celebrex is a drug that is prescribed for inflammation, pain, and stiffness caused by conditions such as arthritis. This drug is a nonsteroidal anti-inflammatory that works by blocking an enzyme that causes inflammation and the pain that accompanies it.

Important information about Celebrex
Celebrex is effective in treating many types of moderate pain, but it does carry some risks. With certain conditions such as heart and circulatory problems, the drug may carry severe risk and should not be used. Women who are pregnant or nursing should be aware that this drug may harm an unborn child, and is passed into breastmilk, so it is not normally prescribed during pregnancy.

What should I discuss with my doctor before taking Celebrex?
Your doctor needs to know about any medications you are taking or plan to take in the near future. If you have a history of heart problems, blood clotting disorder, stroke, liver disease, kidney disease, nasal polyps, or seizures it is important that you discuss this with the doctor, as these conditions carry an added risk factor for Celebrex.

How should I take Celebrex?
You should take Celebrex precisely as your doctor prescribes it. This medication should be taken along with food or milk to decrease the chance of an upset stomach. This medication should not be chewed up or snorted. If your doctor allows you to open the capsules to sprinkle them in food for easier swallowing, be sure to safely dispose of the empty capsule.

What happens if I miss a dose?
Since Celebrex is prescribed on an as-needed basis, most patients do not have a schedule to take this medication. In certain cases doctors will prescribe a daily dosage, however. If you forget to take a scheduled dose, you may take it when you remember, as long as it is not almost time for your next dose. If it is almost time for the next dose, do not take the missed dose and just wait for the next one.

What happens if I overdose?
You should see a medical professional right away if you believe you have overdosed on Celebrex. Possible symptoms of an overdose include extreme sleepiness, stool irregularities, regurgitation, stomach pains, slowed rate of breathing, loss of consciousness, or in very rare cases lapsing into a coma.

What should be avoided while taking Celebrex?
Avoid taking other NSAID medications, including prescription drugs and over the counter anti inflammatory drugs such as ibuprofen. Also avoid drinking alcohol while taking Celebrex as it can cause issues with stomach bleeding. It is best to avoid exposure to sunlight or tanning beds if possible: This drug increases your sensitivity to light so sunburns may occur.

Celebrex side effects
Celebrex side effects are generally quite mild. These include: stomach upset, dizziness, minor skin rash, constipation, diarrhea, painful gas, and tinnitus. Major side effects are quite uncommon, and include inability to breathe normally, loss of balance, vision problems, irregular stools, regurgitation of a dark brown color, a deep cough that leaves traces of blood, irregular urination, and muscular problems like pain, tingling, burning, or extreme weakness.

What other drugs will affect Celebrex?
There are a number of drugs that can affect Celebrex. Tell your physician about each drug you take to avoid problems. If you take antidepressants, notably ones such as Celexa, Cymbalta, Lexapro, Prozac, Zoloft, or Effexor, you may still be able to take this drug but will likely be more susceptible to bleeding or bruising. Other drugs that may affect Celebrex include blood thinners, diuretics, heart medicines, blood pressure medicines, or ACE inhibitors.